Dichloromethane → 1-(4-Chloro-3-trifluoromethyl-phenyl)-3-(5-methyl-1-pyridin-4-ylmethyl-1H-benzoimidazol-4-yl)-urea

HRID 102946Notes

Reaction equation

HRID 102946 reaction equation
[CH3:1][c:2]1[c:3]([NH2:18])[c:4]2[c:5]([n:6]([CH2:9][c:10]3[cH:11][cH:12][n:13][cH:14][cH:15]3)[cH:7][n:8]2)[cH:16][cH:17]1.[Cl:19][c:20]1[c:21]([C:29]([F:30])([F:31])[F:32])[cH:22][c:23]([N:26]=[C:27]=[O:28])[cH:24][cH:25]1.[Cl:33][CH2:34][Cl:35]>>[CH3:1][c:2]1[c:3]([NH:18][C:27]([NH:26][c:23]2[cH:22][c:21]([C:29]([F:30])([F:31])[F:32])[c:20]([Cl:19])[cH:25][cH:24]2)=[O:28])[c:4]2[c:5]([n:6]([CH2:9][c:10]3[cH:11][cH:12][n:13][cH:14][cH:15]3)[cH:7][n:8]2)[cH:16][cH:17]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 27332651-Chloro-4-isocyanato-2-(trifluoromethyl) benzeneHCID 594286405-Methyl-1-(pyridin-4-yl)methyl-1H-benzimidazol-4-ylamine

Product 1

HCID 498059651-(4-Chloro-3-trifluoromethyl-phenyl)-3-(5-methyl-1-pyridin-4-ylmethyl-1H-benzoimidazol-4-yl)-urea

Sources & evidence

ORD record
ord-9539f5bb443648a4b907ac14cbe9b992
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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