HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-Diisopropylaminobutyric acid hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1-Methylpiperidine-3-carboxylic acid hydrochloride | HCID 12514711 | — |
| Reactant | Ethyl 4-diisopropylaminobutyrate | HCID 19900433 | — |
| Product | 4-Diisopropylaminobutyric acid hydrochloride | HCID 86745631 | — |
Reaction Steps
4-Diisopropylaminobutyric acid hydrochloride may be obtained by working according to the method described in Example 4 for the preparation of 1-methyl-3-piperidinecarboxylic acid hydrochloride, but starting with ethyl 4-diisopropylaminobutyrate (9.2 g) and 6 N aqueous hydrochloric acid solution (28.5 cc) and by heating for 6 hours under reflux. 4-Diisopropylaminobutyric acid hydrochloride (8 g), m.p. 136° C., is thereby obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05102890 |
| Source dataset | uspto-grants-1992_04 |
| ORD ID | ord-b915410b6fbb47b2a8b507389b39408f |
| Source note | uspto-grants-1992_04 |