Butyric Acid → 2-Propylimidazo[4,5-b]pyridine

HRID 1029551Notes

Reaction equation

[CH2:1]([C:5]1[NH:6][C:7]2[C:8]([N:13]=1)=[N:9][CH:10]=[CH:11][CH:12]=2)[CH2:2][CH2:3]C.NC1C=NC=CC=1N.C(O)(=O)CCC>>[CH2:1]([C:5]1[NH:6][C:7]2[C:8]([N:13]=1)=[N:9][CH:10]=[CH:11][CH:12]=2)[CH2:2][CH3:3]

Participants

Reactant 3

HCID 264Butyric Acid

HCID 59183,4-Diaminopyridine

HCID 124677102-butyl-1H-imidazo[4,5-b]pyridine

Product 1

HCID 124677082-Propylimidazo[4,5-b]pyridine

Procedure

The title compound was prepared according to the procedure described for the preparation of 2-butylimidazo[4,5-b]pyridine starting with 3,4-diaminopyridine and butyric acid. Yield: 6.60 g (89%) amorphous solid.

Sources & evidence

ORD record: ord-4f5cf04ff17640c98351f89979e408f5
Source dataset: uspto-grants-1992_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05102880

Reaction notes

Loading…