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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 102957Generated: October 25, 2026

Tetrahydrofuran → 2-[1-(4-Amino-phenyl)-2,2,2-trifluoro-1-trifluoromethyl-ethoxymethyl]-pyrrolidine-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/102957

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriphenylphosphineHCID 11776—
Reactantethyl N-ethoxycarbonyliminocarbamateHCID 220568—
Reactanttert-Butyl 2-(hydroxymethyl)pyrrolidine-1-carboxylateHCID 550865—
Reactant2-(4-Aminophenyl)-1,1,1,3,3,3-hexafluoropropan-2-olHCID 577801—
Product2-[1-(4-Amino-phenyl)-2,2,2-trifluoro-1-trifluoromethyl-ethoxymethyl]-pyrrolidine-1-carboxylic acid tert-butyl esterHCID 86590382—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-a386f21dda7a41a6ae4fc510562cbb70
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)