4-(Trifluoromethyl)aniline → HCID 19901121, compound

HRID 1029798Notes

Reaction equation

HRID 1029798 reaction equation
[S:1]1[CH2:4][S:3][C:2]1=[C:5]([C:12](C(OOCC)=O)=[O:13])[C:6]([O:8][CH:9]([CH3:11])[CH3:10])=[O:7].[NH2:20][C:21]1[CH:26]=[CH:25][C:24]([C:27]([F:30])([F:29])[F:28])=[CH:23][CH:22]=1>>[S:3]1[CH2:4][S:1][C:2]1=[C:5]([C:12](=[O:13])[NH:20][C:21]1[CH:26]=[CH:25][C:24]([C:27]([F:28])([F:29])[F:30])=[CH:23][CH:22]=1)[C:6]([O:8][CH:9]([CH3:10])[CH3:11])=[O:7]

Participants

3

Reactant 2

HCID 99644-(Trifluoromethyl)anilineHCID 19901120HCID 19901120, compound

Product 1

HCID 19901121HCID 19901121, compound

Procedure

Following the procedure of Example 18, the titled compound was prepared as a white solid (67%) from isopropyl 2-(1,3-dithietan-2-ylidene)-2-(ethoxycarboxycarbonyl)acetate and 4-aminobenzotrifluoride.

Sources & evidence

ORD record
ord-b7080c081f7b423a891622940e53fe36
Source dataset
uspto-grants-1992_04
Patent number
US05103013

Reaction notes

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