Ethyl 2-(2-aminothiazol-5-ylthio)acetate → {2-[3-[3-(5-Chloro-benzofuran-3-yl)-propyl]-3-(trans-4-methyl-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid
Reaction equation
[CH2:47]([O:48][C:49](=[O:50])[CH2:51][S:52][c:53]1[s:54][c:55]([NH2:56])[n:57][cH:58]1)[CH3:59].[Cl:1][c:2]1[cH:3][c:4]([CH2:5][CH2:6][CH2:10][N:11]([C:12]([NH:13][c:14]2[s:15][c:16]([S:19][CH2:20][C:21](=[O:22])[OH:23])[cH:17][n:18]2)=[O:24])[CH:25]2[CH2:26][CH2:27][CH:28]([CH3:31])[CH2:29][CH2:30]2)[cH:7][cH:8][cH:9]1.[Cl:32][c:33]1[cH:34][cH:35][c:36]2[c:37]([c:38]([CH2:41][CH2:42][C:43]([OH:44])=[O:45])[cH:39][o:40]2)[cH:46]1>>[CH2:10]([N:11]([C:12]([NH:13][c:14]1[s:15][c:16]([S:19][CH2:20][C:21](=[O:22])[OH:23])[cH:17][n:18]1)=[O:24])[CH:25]1[CH2:26][CH2:27][CH:28]([CH3:31])[CH2:29][CH2:30]1)[CH2:42][CH2:41][c:38]1[c:37]2[c:36]([cH:35][cH:34][c:33]([Cl:32])[cH:46]2)[o:40][cH:39]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-a31e65c62b8545aeba72086ade316b7a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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