Vinyl chloroformate → HCID 54478848, compound

Participants

Reaction Steps

A mixture of 2-benzyl-7,7-diphenyl-2,3,3a,4,7,7a-hexahydro-4-1H-isoindolone (3.4 g) and vinyl chloroformate (0.92 cc) in 1,2-dichloroethane (80 cc) is refluxed for 1 hour; the reaction mixture is concentrated to dryness under reduced pressure (2.7 kPa). The residue is crystallized from ethyl ether (20 cc). 7,7-Diphenyl-2-vinyloxycarbonyl-2,3,3a,4,7,7a-hexahydro-4-1H-isoindolone (2.6 g) melting at 162° C. is obtained.

Provenance & Evidence