Ethyl Acetate → HCID 54162423, compound

Participants

Reaction Steps

A solution of 1,1-bis-(3-tolyl)-2-methoxyethanol (24.66 g) (obtained by reaction of (3-tolyl)magnesium bromide on methyl 2-methoxyacetate in tetrahydrofuran) in formic acid (30 cc) is refluxed for 12 hours, cooled and poured into a mixture of saturated sodium carbonate solution (400 cc) and ethyl acetate (400 cc). The organic phase is washed with water (3×300 cc) and with saturated sodium chloride solution (300 cc), then dried and concentrated to dryness under reduced pressure (2.7 kPa) to give bis-(3-tolyl)acetaldehyde (20.45 g) in the form of a yellow oil.

Provenance & Evidence