HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl 2-Chloroethyl Ether → (3aRS,7aRS)-7,7-diphenyl-2-{2-[2-(2-hydroxyethoxy)phenyl]acetyl}-4-perhydroisoindolone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl 2-Chloroethyl Ether | HCID 223538 | — |
| Reactant | (3aRS,7aRS)-7,7-diphenyl-2-(2-hydroxyphenylacetyl)-4-perhydroisoindolone | HCID 67915856 | — |
| Product | (3aRS,7aRS)-7,7-diphenyl-2-{2-[2-(2-hydroxyethoxy)phenyl]acetyl}-4-perhydroisoindolone | HCID 67916033 | — |
Reaction Steps
Following the procedure of Example 102 and using (3aRS,7aRS)-7,7-diphenyl-2-(2-hydroxyphenylacetyl)-4-perhydroisoindolone and 1-benzyloxy-2-chloroethane as starting materials, (3aRS,7aRS)-7,7-diphenyl-2-{2-[2-(2-hydroxyethoxy)phenyl]acetyl}-4-perhydroisoindolone (0.5 g) is obtained in the form of white crystals melting at 150° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05102667 |
| Source dataset | uspto-grants-1992_04 |
| ORD ID | ord-3a13183fc16e4d898ac5e83db5c42817 |
| Source note | uspto-grants-1992_04 |