Hydrochloric Acid → HCID 19900623, compound

Participants

Reaction Steps

A mixture comprising 3.9 g of 2,2-dimethyl-1,3-dioxolan-4-ylmethyl 2,5,7,8-tetramethyl-2-(4',8',12'-trimethyltridecyl)-6-chromanyl carbonate, 15 ml of tetrahydrofuran, 5 ml of methanol and 5 ml of 2 N hydrochloric acid was stirred and heated under reflux for 3 hours. The reaction mixture was dissolved in ether, successively washed with water, an aqueous solution of sodium hydrogencarbonate and water, and dried over magnesium sulfate. After distilling off the solvent, the obtained oily residue was purified by column chromatography (silica gel, hexane : ethyl acetate=3.5:1.5) to thereby give 3.3 g of the title compound as a pale yellow, viscous liquid.

Provenance & Evidence