Hydrochloric Acid → HCID 19900613, compound

Participants

Reaction Steps

A mixture comprising 5.0 g of 2,2-dimethyl-1,3-dioxolan-4-yiethyl 2,5,7,8-tetramethyl-2-(4',8', 12'-trimethyltridecyl)-6-chromanyl carbonate, 20 ml of tetrahydrofuran, 10 ml of methanol and 8 ml of 2N hydrochloric acid was heated under reflux for 3 hours with stirring. Then the reaction mixture was dissolved in ether, successively washed with water, an aqueous solution of sodium hydrogencarbonate and water, and dried. After distilling off the solvent, the obtained oily residue was purified by column chromatography (silica gel, hexane : ethyl acetate=3.5:1.5) to thereby give 4.2 g of the title compound as a pale yellow, viscous liquid.

Provenance & Evidence