Sodium Hydroxide → HCID 178493421, compound

HRID 1030086Notes

Reaction equation

HRID 1030086 reaction equation
C([O:4][C:5]1[CH:10]=[CH:9][C:8]([C:11]2[NH:12][C:13]3[CH:18]=[CH:17][N:16]=[CH:15][C:14]=3[N:19]=2)=[C:7]([O:20][CH3:21])[CH:6]=1)(=O)C.[OH-].[Na+]>CO>[OH:4][C:5]1[CH:10]=[CH:9][C:8]([C:11]2[NH:12][C:13]3[CH:18]=[CH:17][N:16]=[CH:15][C:14]=3[N:19]=2)=[C:7]([O:20][CH3:21])[CH:6]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 178493534HCID 178493534, compound

Product 1

HCID 178493421HCID 178493421, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A mixture of 10 g of 2-(4-acetoxy-2-methoxyphenyl)imidazo(4,5-c)pyridine, 100 ml of methanol and 100 ml of 2N aqueous NaOH solution is allowed to stand at 20° for 16 hours. After the usual work-up, 2-(4-hydroxy-2-methoxyphenyl)imidazo(4,5-c)pyridine is obtained; fumarate, m.p. 255°.

Sources & evidence

ORD record
ord-ceec770444794a73be26142d896ecb90
Source dataset
uspto-grants-1992_04
Patent number
US05104881

Reaction notes

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