HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl fluorosulfate → (2S)-1,1-Dimethyl-2-(4-methoxybenzylthiomethyl)pyrrolidinium fluorosulfonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl fluorosulfate | HCID 9870 | — |
| Reactant | (2S)-2-(4-Methoxybenzylthiomethyl)-1-methylpyrrolidine | HCID 57048351 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | (2S)-1,1-Dimethyl-2-(4-methoxybenzylthiomethyl)pyrrolidinium fluorosulfonate | HCID 14880299 | — |
Reaction Steps
The procedure described in preparation 5-(5) was repeated, but using 740 mg of (2S)-2-(4-methoxybenzyl-thiomethyl)-1-methylpyrrolidine and 243 μl of methyl fluorosulfonate in the presence of 22 ml of methylene chloride, to afford 1.0 g of the title compound as crystals, melting at 150°-153° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05104867 |
| Source dataset | uspto-grants-1992_04 |
| ORD ID | ord-40b3b2208a594933b6641269dec7e68f |
| Source note | uspto-grants-1992_04 |