HCID 19822169, compound → HCID 19822273, compound

HRID 1030379Notes

Reaction equation

HRID 1030379 reaction equation
[OH:1][CH2:2][CH2:3][O:4][C:5]1[C:6]([CH3:34])=[C:7]2[C:12](=[C:13]([CH3:16])[C:14]=1[CH3:15])[O:11][C:10]([CH2:18][O:19][C:20]1[CH:33]=[CH:32][C:23]([CH2:24][CH:25]3[S:29][C:28](=[O:30])[NH:27][C:26]3=[O:31])=[CH:22][CH:21]=1)([CH3:17])[CH:9]=[CH:8]2>[Pd].C(O)C>[OH:1][CH2:2][CH2:3][O:4][C:5]1[C:6]([CH3:34])=[C:7]2[C:12](=[C:13]([CH3:16])[C:14]=1[CH3:15])[O:11][C:10]([CH2:18][O:19][C:20]1[CH:33]=[CH:32][C:23]([CH2:24][CH:25]3[S:29][C:28](=[O:30])[NH:27][C:26]3=[O:31])=[CH:22][CH:21]=1)([CH3:17])[CH2:9][CH2:8]2

Participants

4

Reactant 1

HCID 19822169HCID 19822169, compound

Product 1

HCID 19822273HCID 19822273, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Following the same procedure as described in Example 41, 0.35 g of 5-{4-[6-(2-hydroxyethoxy)-2,5,7,8-tetramethyl-2H-chromen-2-ylmethoxy]benzyl}-thiazolidine-2,4-dione (prepared as described in Example 40), 0.3 g of 10% w/w palladium on activated carbon and 10 ml of ethanol gave the title compound.

Sources & evidence

ORD record
ord-91cc093d2e204e0c82ff2fd3ba394e95
Source dataset
uspto-grants-1992_04
Patent number
US05104888

Reaction notes

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