p-Toluenesulfonic acid monohydrate → HCID 19822239, compound

Participants

Reaction Steps

A mixture of 2.4 g of 4,6-diacetoxy-7-t-butyl-2-methyl-2-(4-nitrophenoxymethyl)chroman (prepared as described in Preparation 56), 0.1 g of p-toluenesulfonic acid monohydrate and 50 ml of benzene was heated under reflux for 1 hour. The reaction solution was cooled, washed with a saturated aqueous solution of sodium bicarbonate, and then with water, and dried over anhydrous sodium sulfate. The solvent was distilled off under reduced pressure, to give the title compound as a yellow oil.

Provenance & Evidence