HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone → Ethyl 2,4-dioxovalerate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | Diethyl Oxalate | HCID 7268 | — |
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | Ethyl orthoformate | HCID 31214 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Ethyl 2,4-dioxovalerate | HCID 69208 | — |
Reaction Steps
Ethyl acetopyruvate was prepared from acetone and diethyl oxalate as described in Org. Synthesis, Coll. Vol. 1, 238 (1958). Further reaction with triethylorthoformate and ammonium chloride in ethanol afforded the known enol ether 1. See L. Claisen, Chem. Ber., 40, 3903 (1907).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05106742 |
| Source dataset | uspto-grants-1992_04 |
| ORD ID | ord-7a775cfdaf0b435fad3101c9450e4d5f |
| Source note | uspto-grants-1992_04 |