3,5-Dichlorophenyl isocyanate → HCID 15616373, compound

HRID 1030475Notes

Reaction equation

HRID 1030475 reaction equation
[NH2:1][CH:2]1[CH2:6][N:5]([CH2:7][CH3:8])[N:4]([CH2:9][CH3:10])[CH2:3]1.[Cl:11][C:12]1[CH:13]=[C:14]([N:19]=[C:20]=[O:21])[CH:15]=[C:16]([Cl:18])[CH:17]=1>C1(C)C=CC=CC=1>[Cl:11][C:12]1[CH:13]=[C:14]([NH:19][C:20]([NH:1][CH:2]2[CH2:6][N:5]([CH2:7][CH3:8])[N:4]([CH2:9][CH3:10])[CH2:3]2)=[O:21])[CH:15]=[C:16]([Cl:18])[CH:17]=1

Participants

4

Reactant 2

HCID 944603,5-Dichlorophenyl isocyanateHCID 5591991,2-Diethyl-4-pyrazolidinamine

Product 1

HCID 15616373HCID 15616373, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent2×

Procedure

A solution of 4-amino-1,2-diethylpyrazolidine (1.26 g, 8.8 mmol) in anhydrous toluene (5 ml) was added to a solution of 3,5-dichlorophenyl isocyanate (1.71 g, 9.1 mmol) in dry toluene (20 ml) and the mixture stirred overnight. The precipitated solid was collected, washed with toluene and dried to give the title compound, 1.94 g. This was converted to the 1:1 maleate, mp 165°-167° C.

Workup

  1. customThe precipitated solid was collected
  2. washwashed with toluene
  3. customdried

Sources & evidence

ORD record
ord-c1640263964249189339766b02c94f9f
Source dataset
uspto-grants-1992_04
Patent number
US05106843

Reaction notes

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