HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalate → N-[[[1-Azabicyclo[2.2.2]octan-3-yl]amino]carbonyl]-2-((cyclopropyl)methoxy)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalate | HCID 71081 | — |
| Reactant | 3-Aminoquinuclidine | HCID 123238 | — |
| Reactant | 2-(Cyclopropylmethoxy)benzamide | HCID 2728029 | — |
| Product | N-[[[1-Azabicyclo[2.2.2]octan-3-yl]amino]carbonyl]-2-((cyclopropyl)methoxy)benzamide | HCID 15616407 | — |
Reaction Steps
The above compound was prepared, following the procedure of Example 1, from 3-aminoquinuclidine (0.63 g, 5 mmol) and crude 2-((cyclopropyl)methoxy)benzamide (1.4 g, ca 5 mmol). The product was converted to the 1:1 oxalate, half hydrate mp 128°-131° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05106843 |
| Source dataset | uspto-grants-1992_04 |
| ORD ID | ord-153d05f3fdb04f178bf69aa717fa28f8 |
| Source note | uspto-grants-1992_04 |