Potassium Hydroxide → HCID 18333054, compound

HRID 1030528Notes

Reaction equation

HRID 1030528 reaction equation
[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([CH2:6][CH:7]([C:13]([O:15]CC)=[O:14])[C:8](=[O:12])[NH:9]2)=[CH:4][CH:3]=1.[OH-].[K+]>C(O)C>[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([CH2:6][CH:7]([C:13]([OH:15])=[O:14])[C:8](=[O:12])[NH:9]2)=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 18332989HCID 18332989, compound

Product 1

HCID 18333054HCID 18333054, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

7-chloro-1,2,3,4-tetrahydro-2-oxo-3-quinoline carboxylic acid, ethyl ester (1.35 g) was dissolved into a solution of potassium hydroxide (0.76 g) in ethyl alcohol (15 ml) at room temperature under stirring. A solid soon separated and was recovered by filtration after 2 hours. The solid was dissolved into cold water and hydrochloric acid was added until precipitation of a white solid took place. The title acid was recovered by filtration and after drying 1.0 g were obtained. M.p. 158°-160° C.

Workup

  1. customA solid soon separated
  2. filtrationwas recovered by filtration after 2 hours
  3. dissolutionThe solid was dissolved into cold water and hydrochloric acid
  4. additionwas added until precipitation of a white solid
  5. filtrationThe title acid was recovered by filtration
  6. customafter drying 1.0 g
  7. customwere obtained

Sources & evidence

ORD record
ord-ad607884bdd9414eb19a814051f3e8a4
Source dataset
uspto-grants-1992_04
Patent number
US05106851

Reaction notes

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