Water → HCID 88467454, compound

HRID 1030536Notes

Reaction equation

HRID 1030536 reaction equation
C(OC([NH:8][CH:9]1[C:46](=[O:47])[N:11]2[C:12]([C:30]([O:32][CH:33]([C:40]3[CH:45]=[CH:44][CH:43]=[CH:42][CH:41]=3)[C:34]3[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=3)=[O:31])=[C:13]([C:16]3[C:19](=[O:20])[C:18](=[O:21])[C:17]=3[O:22][CH2:23][C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[CH2:14][S:15][C@H:10]12)=O)(C)(C)C.O>C(#N)C>[NH2:8][CH:9]1[C:46](=[O:47])[N:11]2[C:12]([C:30]([O:32][CH:33]([C:40]3[CH:45]=[CH:44][CH:43]=[CH:42][CH:41]=3)[C:34]3[CH:35]=[CH:36][CH:37]=[CH:38][CH:39]=3)=[O:31])=[C:13]([C:16]3[C:19](=[O:20])[C:18](=[O:21])[C:17]=3[O:22][CH2:23][C:24]3[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=3)[CH2:14][S:15][C@H:10]12

Participants

4

Reactant 2

HCID 962WaterHCID 88467516HCID 88467516, compound

Product 1

HCID 88467454HCID 88467454, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

Diphenylmethyl 7-(t-butoxycarbonylamino)-3-(2-benzyloxy-3,4-dioxo-1-cyclobutenyl)-3-cephem-4-carboxylate was deprotected with a solution of pTSOH.H2O in acetonitrile as described in the preceding experiment to provide the title compound which was directly used in the next step.

Sources & evidence

ORD record
ord-ec204335f81f488d919141a447248705
Source dataset
uspto-grants-1992_04
Patent number
US05106842

Reaction notes

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