HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylanisole → 4-Bromo-1-methoxy-2-methylbenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylanisole | HCID 33637 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Catalyst | Benzoyl Peroxide | HCID 7187 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | 4-Bromo-1-methoxy-2-methylbenzene | HCID 608315 | 47.1% |
Reaction Steps
A solution of 24 g of 2-methylanisole, 35 g of N-bromosuccinimide and 1.24 g of dibenzoyl peroxide in 150 ml of carbon tetrachloride was heated to boiling under reflux for 12 hours. After cooling the solution was filtered and the filtrate is evaporated. The residue was recrystallized from hexane. There were obtained 18.6 g (47%) of 4-bromo-2-methylanisole as a colorless solid; m.p. 66°-68°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05106878 |
| Source dataset | uspto-grants-1992_04 |
| ORD ID | ord-9f7f8941df204d8c917e52a67d15d7f9 |
| Source note | uspto-grants-1992_04 |