HCID 14839448, compound → HCID 14839449, compound

HRID 1030805Notes

Reaction equation

HRID 1030805 reaction equation
[SH:1][C:2]1[NH:3][C:4]2[C:5]([N:10]=1)=[N:6][CH:7]=[CH:8][CH:9]=2.Cl.[CH:12]1([NH:17][C:18]2[CH:25]=[CH:24][CH:23]=[CH:22][C:19]=2[CH2:20]Cl)[CH2:16][CH2:15][CH2:14][CH2:13]1>C(O)C>[CH:12]1([NH:17][C:18]2[CH:25]=[CH:24][CH:23]=[CH:22][C:19]=2[CH2:20][S:1][C:2]2[NH:3][C:4]3[C:5]([N:10]=2)=[N:6][CH:7]=[CH:8][CH:9]=3)[CH2:16][CH2:15][CH2:14][CH2:13]1

Participants

4

Reactant 2

HCID 14839448HCID 14839448, compoundHCID 178527819HCID 178527819, compound

Product 1

HCID 14839449HCID 14839449, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2-Mercaptoimidazo[4,5-b]pyridine and 2-(N-cyclopentylamino)benzyl chloride hydrochloride were reacted in an aqueous ethanol solution to obtain 2-[2-(N-cyclopentylamino)benzylthio]-imidazo[4,5-b]pyridine in the same manner as in Example 9-(2). The obtained 2-[2-(N-cyclopentylamino)benzylthio]imidazo[4,5-b]pyridine was oxidized by m-chloroperbenzoic acid in chloroform in the same manner as in Example 9-(3) to give 2-[2-(N-cyclopentylamino)benzylsulfinyl]imidazo[4,5-b]pyridine as a pale yellow crystalline product. m.p.: 134° C. (decompn.)

Sources & evidence

ORD record
ord-4673dbd3bdd44fc4a7292467a1a8fffa
Source dataset
uspto-grants-1992_04
Patent number
US05106976

Reaction notes

Loading…