Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methylhydrazine → 1-Amino-3-(4-fluorophenyl)-1-methylthiourea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methylhydrazine | HCID 6061 | — |
| 반응물 | 4-Fluorophenyl isothiocyanate | HCID 15241 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 1-Amino-3-(4-fluorophenyl)-1-methylthiourea | HCID 2363269 | 76.9% |
반응 단계
Following procedures similar to those employed in Step A of Example 2, the reaction of 10.0 g (0.0653 mole) of 4-fluorophenyl isothiocyanate with 3.01 g (0.0654 mole) of methylhydrazine in 100 ml of ethanol yielded 10 g of 4-(4-fluorophenyl)-2-methyl-3-thiosemicarbazide as a solid, mp 148°-150° C. The nmr spectrum was consistent with the proposed structure.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05108486 |
| 출처 데이터셋 | uspto-grants-1992_04 |
| ORD ID | ord-3efbdf90d841442fba4e67203065ce6f |
| 출처 메모 | uspto-grants-1992_04 |