Chlorine → HCID 14460367, compound

HRID 1031050Notes

Reaction equation

[Cl:1]Cl.[CH3:3][C:4]([CH3:45])([CH3:44])[C:5](=[O:43])[CH:6]([N:20]1[CH:23](SC)[CH:22]([CH:26]([O:28][C:29]([O:31][CH2:32][C:33]2[CH:38]=[CH:37][C:36]([N+:39]([O-:41])=[O:40])=[CH:35][CH:34]=2)=[O:30])[CH3:27])[C:21]1=[O:42])[C:7]([O:9][CH2:10][C:11]1[CH:16]=[CH:15][C:14]([N+:17]([O-:19])=[O:18])=[CH:13][CH:12]=1)=[O:8].[N+](C1C=CC(C([O-])=O)=CC=1)([O-])=O>C(Cl)(Cl)(Cl)Cl.C(Cl)Cl>[Cl:1][CH:23]1[N:20]([CH:6]([C:5](=[O:43])[C:4]([CH3:45])([CH3:44])[CH3:3])[C:7]([O:9][CH2:10][C:11]2[CH:16]=[CH:15][C:14]([N+:17]([O-:19])=[O:18])=[CH:13][CH:12]=2)=[O:8])[C:21](=[O:42])[CH:22]1[CH:26]([O:28][C:29]([O:31][CH2:32][C:33]1[CH:38]=[CH:37][C:36]([N+:39]([O-:41])=[O:40])=[CH:35][CH:34]=1)=[O:30])[CH3:27]

Participants

Conditions

Temperature: -60 °C

Procedure

660 μl of a solution of chlorine in carbon tetrachloride containing 850 mg in 10 ml are added at -60° C. to a solution of 244 mg (0.395 mmol) of p-nitrobenzyl 4,4-dimethyl-2-[4-methylthio-3-(1-(p-nitrobenzyloxycarbonyloxy)-ethyl)-2-oxoazetidinyl]-3-oxo-pentanoate-p-nitrobenzoate in 16 ml of methylene chloride. The weakly yellow solution is stirred at -60° C. during the course of 2 hours and the solvent is removed in vacuo, 236 mg of a colorless non-crystalline solid being obtained. IR spectrum in CH2Cl2 : 2930, 2850, 1795, 1765, 1725, 1620, 1530, 1355 cm-1.

Workup

customthe solvent is removed in vacuo, 236 mg of a colorless non-crystalline solid being
customobtained

Sources & evidence

ORD record: ord-43e917bdb7984a1f8b57d4b4a5832b01
Source dataset: uspto-grants-1992_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05108747

Reaction notes

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