Allyl bromide → HCID 86745729, compound

HRID 1031065Notes

Reaction equation

HRID 1031065 reaction equation
[NH2:1][CH:2]([C:21]([O:23][CH2:24][CH3:25])=[O:22])[CH2:3][C:4](=C)[CH2:5][C:6]([NH:17][CH:18]=[O:19])([C:12]([O:14][CH2:15][CH3:16])=[O:13])[C:7]([O:9][CH2:10][CH3:11])=[O:8].ClC(C)=CC.C(Br)C=C>C(OCC)(=O)C.C(O)C>[NH2:1][CH:2]([C:21]([O:23][CH2:24][CH3:25])=[O:22])[CH2:3][CH:4]=[CH:5][C:6]([NH:17][CH:18]=[O:19])([C:12]([O:14][CH2:15][CH3:16])=[O:13])[C:7]([O:9][CH2:10][CH3:11])=[O:8]

Participants

5

Reactant 3

HCID 7841Allyl bromideHCID 1374981-Methyl-1-propenyl chlorideHCID 13588529HCID 13588529, compound

Product 1

HCID 86745729HCID 86745729, compound

Reagents, catalysts & solvents 1

HCID 21584252Ethanol ethylacetateSolvent

Procedure

Using the procedure for the preparation of triethyl 5-amino-1-(formylamino)-3-methylene-1,1,5-pentanetricarboxylate, chloro-methylpropene replaced the allyl bromide to obtain the expected product in the form of an oil with an Rf=0.4 in ethyl acetate/ethanol 4:1.

Sources & evidence

ORD record
ord-7501b0e8c21b4aac8cbce1dc82e5892a
Source dataset
uspto-grants-1992_04
Patent number
US05108990

Reaction notes

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