2-Acetamidophenol → Picolyl chloride hydrochloride

HRID 1031136Notes

Reaction equation

[NH:1]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1O)C(C)=O.[Cl:12]CC1C=CN=CC=1>>[ClH:12].[Cl:12][CH2:10][C:9]1[CH:8]=[CH:7][CH:6]=[CH:5][N:1]=1

Participants

Reactant 2

HCID 119722-Acetamidophenol

HCID 745714-(Chloromethyl)pyridine

Product 1

HCID 23392Picolyl chloride hydrochloride

Procedure

By following the procedure of Example 1, part A, but replacing 4-acetaminophenol with 2-acetaminophenol, and 4-chloromethylpyridine hydrocholoride, with 2-chloromethylpyridine hydrochloride, the title compound is obtained.

Sources & evidence

ORD record: ord-874129ac1cd748ad9ba9701c773ccf0c
Source dataset: uspto-grants-1992_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05109009

Reaction notes

Loading…