Ammonia → HCID 18639818, compound

HRID 1031258Notes

Reaction equation

[C:1]([S:4][CH:5]([CH:10]([C:15]([NH:17][C@H:18]([C:28]([NH:30][CH3:31])=[O:29])[CH2:19][C:20]1[CH:25]=[CH:24][C:23]([O:26][CH3:27])=[CH:22][CH:21]=1)=[O:16])CC(C)C)[CH2:6][C:7]([OH:9])=O)(=[O:3])[CH3:2].[NH3:32]>>[C:1]([S:4][CH:5]([CH2:10][C:15]([NH:17][C@H:18]([C:28]([NH:30][CH3:31])=[O:29])[CH2:19][C:20]1[CH:21]=[CH:22][C:23]([O:26][CH3:27])=[CH:24][CH:25]=1)=[O:16])[CH:6]([CH2:19][CH:20]([CH3:25])[CH3:21])[C:7]([NH2:32])=[O:9])(=[O:3])[CH3:2]

Participants

Reactant 2

HCID 222Ammonia

HCID 18639816HCID 18639816, compound

Product 1

HCID 18639818HCID 18639818, compound

Procedure

The title compound, m.p. 235°-240° C., was prepared from the compound of Example 5 and ammonia by an analogous procedure to that described in Example 11.

Sources & evidence

ORD record: ord-6c15bfd433024a28a9dd68e82b50c924
Source dataset: uspto-grants-1992_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05109000

Reaction notes

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