HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 15030135, compound → HCID 15030120, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 15030135 | HCID 15030135 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 15030120 | HCID 15030120 | 90.2% |
Reaction Steps
Similarly 7.9 g of (+)-3-(4-morpholinylmethyl)-5-methyl-6-phenylthio-2,3-dihydropyrrolo[1,2,3-de]-1,4-benzoxazine in 300 ml of ethanol was reduced with three teaspoons of Raney nickel to give 5.1 g of (+)-3-(4-morpholinylmethyl)-5-methyl-2,3-dihydropyrrolo[1,2,3-de]-1,4-benzoxazine, [α]D25 =+64.8°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05109135 |
| Source dataset | uspto-grants-1992_04 |
| ORD ID | ord-4a0a62453d7f4c09a4e57fb7d1d24a2d |
| Source note | uspto-grants-1992_04 |