Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1031278Generated: October 25, 2026

4-Toluenesulfonyl chloride → N-(4-iodophenyl)-4-methylbenzenesulfonamide

https://huagongshe.com/reaction/1031278

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Toluenesulfonyl chlorideHCID 7397—
Reactant4-IodoanilineHCID 10893—
ReagentSodium BicarbonateHCID 516892—
SolventAcetoneHCID 180—
SolventWaterHCID 962—
SolventPentaethylene glycolHCID 62551—
ProductN-(4-iodophenyl)-4-methylbenzenesulfonamideHCID 29362890%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1021/co400012m
Source dataset39 compound library from "Building a Sulfonamide Library by Eco-Friendly Flow Synthesis"
ORD IDord-00b28c352e6a453398fad16ac35a55c6
Source note39 compound library from "Building a Sulfonamide Library by Eco-Friendly Flow Synthesis"