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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1031281Generated: October 30, 2026

2-Aminobiphenyl → N-Biphenyl-2-yl-4-methyl-benzenesulfonamide

https://huagongshe.com/reaction/1031281

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-AminobiphenylHCID 7015—
Reactant4-Toluenesulfonyl chlorideHCID 7397—
ReagentSodium BicarbonateHCID 516892—
SolventAcetoneHCID 180—
SolventWaterHCID 962—
SolventPentaethylene glycolHCID 62551—
ProductN-Biphenyl-2-yl-4-methyl-benzenesulfonamideHCID 81864798%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1021/co400012m
Source dataset39 compound library from "Building a Sulfonamide Library by Eco-Friendly Flow Synthesis"
ORD IDord-426951e60a664643a083d7159cbb3384
Source note39 compound library from "Building a Sulfonamide Library by Eco-Friendly Flow Synthesis"