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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1031284Generated: October 29, 2026

Glycine → N-((4-Methylphenyl)sulfonyl)glycine

https://huagongshe.com/reaction/1031284

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGlycineHCID 750—
Reactant4-Toluenesulfonyl chlorideHCID 7397—
ReagentSodium BicarbonateHCID 516892—
SolventAcetoneHCID 180—
SolventWaterHCID 962—
SolventPentaethylene glycolHCID 62551—
ProductN-((4-Methylphenyl)sulfonyl)glycineHCID 7065398%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1021/co400012m
Source dataset39 compound library from "Building a Sulfonamide Library by Eco-Friendly Flow Synthesis"
ORD IDord-5134201167564f99aaefb2c648def79d
Source note39 compound library from "Building a Sulfonamide Library by Eco-Friendly Flow Synthesis"