Methanesulfenyl chloride, trifluoro- → HCID 54297913, compound

HRID 1031328Notes

Reaction equation

HRID 1031328 reaction equation
[F:1][C:2]([F:6])([F:5])[S:3]Cl.[Cl:7][CH2:8][CH2:9][CH2:10][C:11]1[C:12]([F:32])=[C:13]([C:18]([C:20]2[CH:25]=[CH:24][C:23]([F:26])=[C:22]([CH2:27][CH2:28][CH2:29][Cl:30])[C:21]=2[F:31])=[O:19])[CH:14]=[CH:15][C:16]=1[F:17]>C(Cl)Cl>[Cl:30][CH2:29][CH2:28][CH:27]([C:22]1[C:21]([F:31])=[C:20]([C:18]([C:13]2[CH:14]=[CH:15][C:16]([F:17])=[C:11]([CH:10]([S:3][C:2]([F:6])([F:5])[F:1])[CH2:9][CH2:8][Cl:7])[C:12]=2[F:32])=[O:19])[CH:25]=[CH:24][C:23]=1[F:26])[S:3][C:2]([F:6])([F:5])[F:1]

Participants

4

Reactant 2

HCID 67900Methanesulfenyl chloride, trifluoro-HCID 53666938HCID 53666938, compound

Product 1

HCID 54297913HCID 54297913, compoundYield 51.9%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

75 g (0.55 mol) of trifluoromethylsulphenyl chloride are added at 20 to 25° C. with stirring to a solution of 43 g (0.2 mol) of 3-chloropropyl-2,4-difluorophenyl ketone in 100 ml of methylene chloride. The mixture is stirred at room temperature for 108 hours and then concentrated by stripping off the solvent under reduced pressure. 63 g of (3-chloro-1-trifluoromethylmercapto-propyl)-2,4-difluorophenyl ketone are obtained.

Workup

  1. concentrationconcentrated

Sources & evidence

ORD record
ord-88be4e7db8944e2cac3b3c61adc7a94e
Source dataset
uspto-grants-1990_09
Patent number
US04954162

Reaction notes

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