4-Methoxy-6-methylpyrimidin-2-amine → HCID 13342739, compound

HRID 1031340Notes

Reaction equation

HRID 1031340 reaction equation
[CH3:1][N:2]1[C:6]([S:7](=[O:12])(=[O:11])[N:8]([CH3:10])[CH3:9])=[C:5]([S:13]([N:16]=[C:17]=[O:18])(=[O:15])=[O:14])[C:4]([CH3:19])=[N:3]1.[NH2:20][C:21]1[N:26]=[C:25]([O:27][CH3:28])[CH:24]=[C:23]([CH3:29])[N:22]=1>>[CH3:28][O:27][C:25]1[CH:24]=[C:23]([CH3:29])[N:22]=[C:21]([NH:20][C:17]([NH:16][S:13]([C:5]2[C:4]([CH3:19])=[N:3][N:2]([CH3:1])[C:6]=2[S:7](=[O:11])(=[O:12])[N:8]([CH3:10])[CH3:9])(=[O:15])=[O:14])=[O:18])[N:26]=1

Participants

3

Reactant 2

HCID 5872364-Methoxy-6-methylpyrimidin-2-amineHCID 22167588HCID 22167588, compound

Product 1

HCID 13342739HCID 13342739, compound

Procedure

From the compound as prepared above, following the procedures of Examples 1 and 2, there was synthesized 1,3-dimethyl-5-dimethylsulfamoylpyrazole-4-sulfonyl isocyanate, which was in turn allowed to react with 2-amino-4-methoxy-6-methylpyrimidine to obtain the title compound. m.p. 215°-217° C.,

Workup

  1. customFrom the compound as prepared above,

Sources & evidence

ORD record
ord-4f4ba3ab61ed48d685e4afb3a859abea
Source dataset
uspto-grants-1990_09
Patent number
US04954164

Reaction notes

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