HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Benzylthio-6,7-dichloro-5-methyl-1,2,4-triazolo[1,5-a]pyrimidine → 2-Benzylthio-6-chloro-5-methyl-1,2,4-triazolo[1,5-a]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Benzylthio-6,7-dichloro-5-methyl-1,2,4-triazolo[1,5-a]pyrimidine | HCID 10782275 | — |
| Catalyst | Zinc copper couple | HCID 10290809 | — |
| Product | 2-Benzylthio-6-chloro-5-methyl-1,2,4-triazolo[1,5-a]pyrimidine | HCID 10493760 | 88% |
Reaction Steps
This material was prepared by reduction of 2-benzylthio-6,7-dichloro-5-methyl-1,2,4-triazolo[1,5-a]pyrimidine with zinc-copper couple following the general procedure described in Example 21. The desired product was isolated in 88% yield as a solid, m.p. 160°-161° C. IR and 1H NMR spectra were in agreement with the assigned structure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04954163 |
| Source dataset | uspto-grants-1990_09 |
| ORD ID | ord-789baba732404cc4baec45c7b1fdf739 |
| Source note | uspto-grants-1990_09 |