1,1,1-Trifluoro-2,4-pentanedione → HCID 14155097, compound

HRID 1031357Notes

Reaction equation

HRID 1031357 reaction equation
[NH2:1][C:2]1[N:6]=[C:5]([S:7][CH2:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[NH:4][N:3]=1.[F:15][C:16]([F:24])([F:23])[C:17](=O)[CH2:18][C:19](=O)[CH3:20]>>[CH2:8]([S:7][C:5]1[N:6]=[C:2]2[N:1]=[C:19]([CH3:20])[CH:18]=[C:17]([C:16]([F:24])([F:23])[F:15])[N:3]2[N:4]=1)[C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1

Participants

3

Reactant 2

HCID 739431,1,1-Trifluoro-2,4-pentanedioneHCID 178509291HCID 178509291, compound

Product 1

HCID 14155097HCID 14155097, compoundYield 84%

Procedure

This material was prepared in 84% yield from 3-amino-5-benzylthio-1,2,4-triazole and 1,1,1-trifluoro2,4-pentanedione following the general procedure described in EXAMPLE 34. The product was purified by recrystallization from benzene-hexane to yield a tan solid, m.p. 83.5°-84.5° C. IR, 1H NMR and 19F NMR spectra were in agreement with the assigned structure.

Workup

  1. customThe product was purified by recrystallization from benzene-hexane
  2. customto yield a tan solid, m.p. 83.5°-84.5° C

Sources & evidence

ORD record
ord-d820502e95fe4f4db577b3db8399d563
Source dataset
uspto-grants-1990_09
Patent number
US04954163

Reaction notes

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