Acetyl chloride → 2-Acetoxymethyl-6-chloroaniline

HRID 1031389Notes

Reaction equation

HRID 1031389 reaction equation
[NH2:1][C:2]1[C:9]([Cl:10])=[CH:8][CH:7]=[CH:6][C:3]=1[CH2:4][OH:5].[C:11](Cl)(=[O:13])[CH3:12]>>[C:11]([O:5][CH2:4][C:3]1[CH:6]=[CH:7][CH:8]=[C:9]([Cl:10])[C:2]=1[NH2:1])(=[O:13])[CH3:12]

Participants

3

Reactant 2

HCID 6367Acetyl chlorideHCID 14155407(2-Amino-3-chlorophenyl)methanol

Product 1

HCID 141554092-Acetoxymethyl-6-chloroaniline

Procedure

This material was prepared from 2-amino-3-chlorobenzyl alcohol and acetyl chloride by the general procedure outlined in Example 98. The product was isolated as an amber oil and was characterized by IR and 'H NMR spectroscopy and combustion analysis.

Workup

  1. customThe product was isolated as an amber oil

Sources & evidence

ORD record
ord-e4c02dfb37804284ae2cfa31984d1908
Source dataset
uspto-grants-1990_09
Patent number
US04954163

Reaction notes

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