Pyridine → HCID 178521792, compound

Participants

Reaction Steps

36.6 g of 5-amino-2-mercaptobenzimidazole and 17.1 ml of pyridine were added to 250 ml of N,N-dimethylacetamide. 34.4 g of phenyl chloroformate was added dropwise to the admixture at room temperature. The admixture was then stirred at room temperature for 1.5 hours. The solution was added to 1.5 l of ice water. The resulting crystal was filtered off. The crystal was recrystallized from acetonitrile to obtain 47.7 g of 2-mercapto-5-phenoxycarbonylaminobenzimidazole.

Provenance & Evidence