6-(4-chloro-3-nitrophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one → HCID 178429568, compound

HRID 1031466Notes

Reaction equation

HRID 1031466 reaction equation
Cl[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]([CH3:15])[CH2:10][C:11](=[O:14])[NH:12][N:13]=2)=[CH:4][C:3]=1[N+:16]([O-:18])=[O:17].[NH2:19][CH2:20][CH2:21][CH2:22][C:23]1[N:24]=[CH:25][NH:26][CH:27]=1>O1CCOCC1>[NH:26]1[CH:27]=[C:23]([CH2:22][CH2:21][CH2:20][NH:19][C:2]2[CH:7]=[CH:6][C:5]([C:8]3[CH:9]([CH3:15])[CH2:10][C:11](=[O:14])[NH:12][N:13]=3)=[CH:4][C:3]=2[N+:16]([O-:18])=[O:17])[N:24]=[CH:25]1

Participants

4

Reactant 2

HCID 28744326-(4-chloro-3-nitrophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-oneHCID 178510931HCID 178510931, compound

Product 1

HCID 178429568HCID 178429568, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

2.67 g (10 mmol) of 6-(4-chloro-3-nitro-phenyl)-5-methyl-4,5-dihydro-3(2H)-pyridazinone are boiled under reflux with 2.5 g (20 mmol) of 4-(3-aminopropyl)-1H-imidazole in 50 ml of dioxane for 5 hours.

Sources & evidence

ORD record
ord-d435fa2448574e9c80919c07c97037aa
Source dataset
uspto-grants-1990_09
Patent number
US04954501

Reaction notes

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