Nitric Acid → HCID 14459494, compound

HRID 1031471Notes

Reaction equation

HRID 1031471 reaction equation
[Cl:1][C:2]1[CH:15]=[CH:14][C:5]([C:6]([CH:8]2[CH2:12][O:11][C:10](=[O:13])[CH2:9]2)=[O:7])=[CH:4][CH:3]=1.[N+:16]([O-])([OH:18])=[O:17]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([CH:8]2[CH2:12][O:11][C:10](=[O:13])[CH2:9]2)=[O:7])=[CH:14][C:15]=1[N+:16]([O-:18])=[O:17]

Participants

3

Reactant 2

HCID 944Nitric AcidHCID 133712434-(4-Chlorobenzoyl)oxolan-2-one

Product 1

HCID 14459494HCID 14459494, compound

Procedure

3.37 g (15 mmol) of 4-(4-chlorobenzoyl)-tetrahydrofuran-2-one are added portion wise to 30 ml of nitric acid (100%) at -15° C. The temperature should not exceed -5° C. Stirring is continued for 30 minutes after all the compound has been added and the mixture is then poured out on 300 ml of ice water and the solid which has precipitated is separated by suction filtration and washed with water.

Workup

  1. customexceed -5° C
  2. additionafter all the compound has been added
  3. customthe solid which has precipitated
  4. customis separated by suction filtration
  5. washwashed with water

Sources & evidence

ORD record
ord-e5cdd087693047d5a063fef0e4d0352b
Source dataset
uspto-grants-1990_09
Patent number
US04954501

Reaction notes

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