Benzenesulfonyl chloride → 2-Bromobenzoic acid 2-phenylsulfonylhydrazide

Participants

Reaction Steps

To a solution of 2-bromobenzoic acid hydrazide (132 g) in pyridine (1.21), cooled to about 10° C. with an ice bath, was added benzenesulfonyl chloride (78.3 ml). After complete addition, the reaction was stirred at ambient temperature for 4 hours, and then poured into ice-HCl to precipitate a solid (135 g). The solid was recrystallized from isopropanol to yield 125 g of 2-bromobenzoic acid 2-phenylsulfonylhydrazide, m.p. 154°-156° C.

Provenance & Evidence