反应详情

Methyl-2-(3-nitrobenzyliden)acetoacetate is added to 1,3-diphenyl-5-pyrazolamine (0.010 mol) in ethanol (16 ml) and refluxed for 90 minutes under nitrogen. After cooling to room temperature, the solvent is evaporated under reduced pressure, the residue is taken up in ethyl ether, discarding the insolubles, and then the solvent is evaporated. Upon crystallization from methanol, the product of the title is obtained. M.p. 186°-189° C.

1. temperaturerefluxed for 90 minutes under nitrogen
2. customthe solvent is evaporated under reduced pressure
3. customthe solvent is evaporated
4. customUpon crystallization from methanol
5. customthe product of the title is obtained