Methylhydrazine → 3-Isopropyl-1-methyl-1H-pyrazol-5-amine

HRID 1031534Notes

Reaction equation

HRID 1031534 reaction equation
[CH3:1][CH:2]([CH3:8])[C:3](=O)[CH2:4][C:5]#[N:6].[CH3:9][NH:10][NH2:11]>C(O)(=O)C>[CH3:9][N:10]1[C:5]([NH2:6])=[CH:4][C:3]([CH:2]([CH3:8])[CH3:1])=[N:11]1

Participants

4

Reactant 2

HCID 6061MethylhydrazineHCID 101299214-Methyl-3-oxopentanenitrile

Product 1

HCID 27594993-Isopropyl-1-methyl-1H-pyrazol-5-amine

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

4-Methyl-3-oxo-pentanenitrile (39.58 g; 0,356 mol) dissolved in glacial acetic acid (400 ml) and methylhydrazine (18.05 g; 0.382 mol) is added thereto, at 15°-20° C.

Workup

  1. customat 15°-20° C.

Sources & evidence

ORD record
ord-594228734e35484e99c97338a95f515f
Source dataset
uspto-grants-1990_09
Patent number
US04954508

Reaction notes

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