5-Hexenoic Acid → Methyl 5-Hexenoate

HRID 1031588노트

반응식

HRID 1031588 반응식
[C:1]([OH:8])(=[O:7])[CH2:2][CH2:3][CH2:4][CH:5]=[CH2:6].O.[C:10]1(C)C(S(O)(=O)=O)=CC=CC=1>CO>[C:1]([O:8][CH3:10])(=[O:7])[CH2:2][CH2:3][CH2:4][CH:5]=[CH2:6]

참가 물질

4

반응물 2

HCID 153085-Hexenoic AcidHCID 124969952-Methylbenzenesulfonic acid hydrate

생성물 1

HCID 520082Methyl 5-Hexenoate수율 84%

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

5-Hexenoic acid (4.9 g, 42.9 mmol) was refluxed in 80 ml of methanol with catalytic p toluene sulfonic acid monohydrate for 40 hours. The solution was cooled and concentrated then poured into ether/water. The ether layer was dried over sodium sulfate and concentrated to give 4.6 g (35.9 mmol), 84% of the title compound.

후처리

  1. temperatureThe solution was cooled
  2. concentrationconcentrated
  3. additionthen poured into ether/water
  4. dry with materialThe ether layer was dried over sodium sulfate
  5. concentrationconcentrated

출처 및 근거

ORD 기록
ord-50017d6bfcd24e6fb6d6b4362a94966e
출처 데이터셋
uspto-grants-1990_09
특허 번호
US04954520

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