Dicyclohexylcarbodiimide → HCID 67869586, compound

HRID 1031608Notes

Reaction equation

HRID 1031608 reaction equation
[CH3:1][N:2]([CH2:4][CH:5]1[C:14]2[C:9](=[C:10]([O:15][CH3:16])[CH:11]=[CH:12][CH:13]=2)[CH2:8][CH2:7][NH:6]1)[CH3:3].[Cl:17][C:18]1[CH:19]=[C:20]([CH2:25][C:26](O)=[O:27])[CH:21]=[CH:22][C:23]=1[Cl:24].C1(N=C=NC2CCCCC2)CCCCC1>C(Cl)Cl>[CH3:3][N:2]([CH2:4][C:5]1([C:26](=[O:27])[CH2:25][C:20]2[CH:21]=[CH:22][C:23]([Cl:24])=[C:18]([Cl:17])[CH:19]=2)[C:14]2[C:9](=[C:10]([O:15][CH3:16])[CH:11]=[CH:12][CH:13]=2)[CH2:8][CH2:7][NH:6]1)[CH3:1]

Participants

5

Reactant 3

HCID 10868DicyclohexylcarbodiimideHCID 798743,4-Dichlorophenylacetic acidHCID 22168029HCID 22168029, compound

Product 1

HCID 67869586HCID 67869586, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Prepared as Ex. No. 1, from 1.2 g (5.45 mmoles) of 1-dimethylaminomethyl-5-methoxy-1,2,3,4-tetrahydroisoquinoline, 1.3 g (6.37 mmoles) of 3,4-dichlorophenylacetic acid and 2.4 g (11.70 mmoles) of dicyclohexylcarbodiimide in 50 ml of dry methylene chloride.

Workup

  1. customPrepared as Ex

Sources & evidence

ORD record
ord-e56876980530451e9154e3acb9e0fc73
Source dataset
uspto-grants-1990_09
Patent number
US04954509

Reaction notes

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