Sodium Hydroxide → HCID 14052773, compound

HRID 1031647Notes

Reaction equation

HRID 1031647 reaction equation
[C:1]([CH:3]([O:11][N:12]=[C:13]([C:22]1[CH:27]=[CH:26][C:25]([O:28][CH3:29])=[CH:24][CH:23]=1)[C:14]1[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=1)[CH2:4][CH2:5][C:6]([O:8]CC)=[O:7])#[N:2].[OH-].[Na+]>O1CCOCC1>[C:1]([CH:3]([O:11][N:12]=[C:13]([C:14]1[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=1)[C:22]1[CH:27]=[CH:26][C:25]([O:28][CH3:29])=[CH:24][CH:23]=1)[CH2:4][CH2:5][C:6]([OH:8])=[O:7])#[N:2]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 14052772HCID 14052772, compound

Product 1

HCID 14052773HCID 14052773, compoundYield 97.8%

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

3.96 g of the 4,4'-dimethoxybenzophenone O-(1-cyano-3-ethoxycarbonylpropyl)oxime was dissolved in 20 ml of dioxane and 3 mil of a 5 N aqueous solution of caustic soda was added thereto. Then the mixture was allowed to react at 20 C. for five hours. After the completion of the reaction, the reaction mixture was acidified and extracted with ethyl acetate. Thus 3.6 g of the title compound was obtained in the form of a colorless oily product.

Workup

  1. customto react at 20 C
  2. customAfter the completion of the reaction
  3. extractionextracted with ethyl acetate

Sources & evidence

ORD record
ord-46e1c7fa22fd4575b2de8e66843ce3cd
Source dataset
uspto-grants-1990_09
Patent number
US04954523

Reaction notes

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