Bromine → HCID 22168216, compound

HRID 1031733Notes

Reaction equation

[C:1]([C:4]1[C:9](=[O:10])[C:8]2[CH:11]=[C:12]([O:20][C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)[C:13]([NH:15][S:16]([CH3:19])(=[O:18])=[O:17])=[CH:14][C:7]=2[O:6][CH:5]=1)(=[O:3])[CH3:2].[Br:27]Br>>[Br:27][CH2:2][C:1]([C:4]1[C:9](=[O:10])[C:8]2[CH:11]=[C:12]([O:20][C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)[C:13]([NH:15][S:16]([CH3:19])(=[O:17])=[O:18])=[CH:14][C:7]=2[O:6][CH:5]=1)=[O:3]

Participants

Reactant 2

HCID 24408Bromine

HCID 14722397HCID 14722397, compound

Product 1

HCID 22168216HCID 22168216, compound

Procedure

3-Acetyl-7-methylsulfonylamino-6-phenoxy-4H-1-benzopyran-4-one was reacted with bromine to obtain 3-(2-bromoacetyl)-7-methylsulfonylamino-6-phenoxy-4H-1-benzopyran-4-one. It was reacted with thioformamide to obtain 7-methylsulfonylamino-6-phenoxy-3-(thiazol-4-yl)-4H-1-benzopyran-4-one.

Sources & evidence

ORD record: ord-010454818ac14ab581e5071f0846ef2b
Source dataset: uspto-grants-1990_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04954518

Reaction notes

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