反应详情

To the compound (I) (2.84 g), 4 N hydrogen chloride/1,4-dioxane solution (35 ml) under room temperature was added and the mixture was stirred at the same temperature for 2 hours. The mixture was concentrated under a reduced pressure, and the residue washed with ethyl ether, followed by filtration to give N-(4-aminomethylbenzoyl)-L-phenylalanine amide hydrochloride (2.32 g) as a white powder.

1. concentrationThe mixture was concentrated under a reduced pressure
2. washthe residue washed with ethyl ether
3. filtrationfollowed by filtration