反应详情

To the compound (III) (2.29 g) was added 4N hydrogen chloride/1,4-dioxane solution (23 ml), and the mixture was stirred at room temperature for one hour. The solvent was evaporated under a reduced pressure, and the residue was washed with ethyl ether and filtered to give N-(trans-4-aminomethylcyclohexylcarbonyl)-L-phenylalanine methylamide hydrochloride (2.03 g) as a white powder.

1. customThe solvent was evaporated under a reduced pressure
2. washthe residue was washed with ethyl ether
3. filtrationfiltered