HCID 14670764, compound → HCID 14670765, compound

HRID 1031887Notes

Reaction equation

HRID 1031887 reaction equation
[F:1][C:2]([F:19])([F:18])[O:3][C:4]1[CH:5]=[C:6]([N+:15]([O-])=O)[CH:7]=[CH:8][C:9]=1[O:10][C:11]([F:14])([F:13])[F:12].[H][H]>CO.[Ni]>[F:1][C:2]([F:18])([F:19])[O:3][C:4]1[CH:5]=[C:6]([CH:7]=[CH:8][C:9]=1[O:10][C:11]([F:12])([F:13])[F:14])[NH2:15]

Participants

5

Reactant 2

HCID 14670764HCID 14670764, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 14670765HCID 14670765, compoundYield 92.7%

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 887MethanolSolvent

Procedure

291 g of the 3,4-bistrifluoromethoxynitrobenzene thus obtained were hydrogenated with 20 bar of hydrogen in the course of 3 hours at 40° C. in 500 ml of methanol with the addition of 10 g of Raney nickel. After filtering off the catalyst with suction, the filtrate was fractionally distilled and 242 g of 3,4-bistrifluoromethoxyaniline were obtained.

Workup

  1. filtrationAfter filtering off the catalyst with suction
  2. distillationthe filtrate was fractionally distilled

Sources & evidence

ORD record
ord-e70d523599da4a3889bcaeb9ec54ca10
Source dataset
uspto-grants-1990_09
Patent number
US04956370

Reaction notes

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