Hydrogen Peroxide → HCID 15106994, compound

Participants

Reaction Steps

To the solution of benzyl 6-cyano-1,2,3,4-tetrahydroquino- line-8-carboxylate (2.5 g) in ethanol (20 ml) was added 35% hydrogen peroxide solution (3 ml) and 6 N sodium hydroxide solution (0.33 ml). The reaction mixture was stirred at 40°-45° C. for 7 hours. The resulting precipitate was collected by filtration and washed with ethanol to give benzyl 6-carbamoyl-1,2,3,4-tetrahydroquinoline-8-carboxylate (1.10 g, 41.7%).

Provenance & Evidence